My niece has an IQ of 125. Her interests lie in the field of mathematics. Does Harvard require a certain IQ s?

My 16 year old niece is an all A student and has made the Headmasters list every year since she was in 1st grade at a very good private school in S.C. She wants to go to Harvard, but she is from the south and people have told her that southerners don't do well in Ivy League schools. Do you think her IQ is high enough? Do you think being a southerner would be a handicap for her?